(2021 - Current) Most recently, I’ve been working on courses and tools to help bridge bioinformatics knowledge gaps (Savonen et al. 2022).

(2018 - 2021) At the Childhood Cancer Data Lab, I helped equip childhood cancer researchers to use data science to empower their research Shapiro et al. (2021).

(2015 - 2018) In grad school, I worked on DNA methylation data in Parkinson’s disease (Kochmanski, Savonen, and Bernstein 2019).

(2013 - 2015) I started out in neuroscience studying the transcriptomics of drug addiction Saad et al. (2019).

Full list of publications

Bannon, Michael J., Candace L. Savonen, Zachary J. Hartley, Magen M. Johnson, and Carl J. Schmidt. 2015. “Investigating the Potential Influence of Cause of Death and Cocaine Levels on the Differential Expression of Genes Associated with Cocaine Abuse.” Edited by Z. Carl Lin. PLOS ONE 10 (2): e0117580. https://doi.org/10.1371/journal.pone.0117580.
Bannon, Michael J., Candace L. Savonen, Hui Jia, Fabien Dachet, Steven D. Halter, Carl J. Schmidt, Leonard Lipovich, and Gregory Kapatos. 2015. “Identification of Long Noncoding RNAs Dysregulated in the Midbrain of Human Cocaine Abusers.” Journal of Neurochemistry 135 (1): 50–59. https://doi.org/10.1111/jnc.13255.
Dang, Mai T., Michael V. Gonzalez, Krutika S. Gaonkar, Komal S. Rathi, Patricia Young, Sherjeel Arif, Li Zhai, et al. 2021. “Macrophages in SHH Subgroup Medulloblastoma Display Dynamic Heterogeneity That Varies with Treatment Modality.” Cell Reports 34 (13): 108917. https://doi.org/10.1016/j.celrep.2021.108917.
Dang, Mai T., Michael Gonzalez, Krutika S. Gaonkar, Komal S. Rathi, Patricia Young, Sherjeel Arif, Li Zhai, et al. 2020. “Single-Cell Transcriptomic Profile Reveals Macrophage Heterogeneity in Medulloblastoma and Their Treatment-Dependent Recruitment,” February. https://doi.org/10.1101/2020.02.12.945642.
Kochmanski, Joseph, Candace Savonen, and Alison I. Bernstein. 2019. “A Novel Application of Mixed Effects Models for Reconciling Base-Pair Resolution 5-Methylcytosine and 5-Hydroxymethylcytosine Data in Neuroepigenetics.” Frontiers in Genetics 10 (September). https://doi.org/10.3389/fgene.2019.00801.
Saad, Manal H., Matthew Rumschlag, Michael H. Guerra, Candace L. Savonen, Alaina M. Jaster, Philip D. Olson, Adnan Alazizi, et al. 2019. “Differentially Expressed Gene Networks, Biomarkers, Long Noncoding RNAs, and Shared Responses with Cocaine Identified in the Midbrains of Human Opioid Abusers.” Scientific Reports 9 (1). https://doi.org/10.1038/s41598-018-38209-8.
Saad, Manal H., Candace L. Savonen, Matthew Rumschlag, Sokol V. Todi, Carl J. Schmidt, and Michael J. Bannon. 2018. “Opioid Deaths: Trends, Biomarkers, and Potential Drug Interactions Revealed by Decision Tree Analyses.” Frontiers in Neuroscience 12 (October). https://doi.org/10.3389/fnins.2018.00728.
Savonen, Candace, Carrie Wright, Ava M. Hoffman, John Muschelli, Katherine Cox, Frederick J. Tan, and Jeffrey T. Leek. 2022. “Open-Source Tools for Training Resources – OTTR.” https://arxiv.org/abs/2203.07083.
Shapiro, Joshua, Candace Savonen, Chante Bethell, Krutika Gaonkar, Yuankun Zhu, Miguel Brown, Nhat Duong, et al. 2021. OMIC-14. OPENPBTA: AN OPEN PEDIATRIC BRAIN TUMOR ATLAS.” Neuro-Oncology 23 (Supplement_1): i40–40. https://doi.org/10.1093/neuonc/noab090.161.